Emotional Regulation Technique May Be Effective In Disrupting Compulsive Cocaine Addiction

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Emotional regulation strategies, known as cognitive reassessments, have helped reduce the usual increased attention paid to drug-related signals and situations in cocaine addicts, according to researchers from Mount Sinai. In an article published in the study. PNASThe team said disruption of this form of habit, mediated by the brain’s prefrontal cortex (PFC), is characteristic of patients and plays an important role in reducing obsessive-compulsive drug-seeking behaviors and recurrences. , a long-standing challenge. Suggested that there is a possibility of realization. Addiction.

“Recurrent Addiction It is often caused by an increased attentional bias towards drug-related cues, such as vision, smell, conversation, and reminders of previous drug use, ”said lead author Dr Muhammad A Parvaz, assistant professor. A PhD in Psychiatry and Neuroscience at Icahn School of Medicine at Mount Sinai is studying brain-based behavioral markers that can inform and monitor drug treatment and its consequences. Drug-related clues Cognitive reassessment This can disrupt the brain’s automatic attentional bias towards these signals and potentially lead to a decrease in compulsive drug-seeking behavior in patients, even outside of the lab. Substance use disorder

Cocaine is a powerful central nervous system stimulant which, when misused, has serious health risks and side effects. Cocaine poisoning is recognized as a treatment resistant disorder and is prevalent nationally and globally. In the United States only, annually due to severe symptoms (primarily cardiovascular) associated with cocaine use. Hundreds of thousands of people are treated in the emergency room. Chronic substance abuse, such as cocaine, directs the brain’s attention system to pay increased attention to drug-related signals in the environment (also known as attention bias). This is considered a risk factor for recurrence.

In this study, researchers from Mount Sinai hypothesized that cognitive reassessment could disrupt the allocation of usually increased attention to drug-related signals in people with cocaine use disorders. Did. Cognitive reassessment is an emotional regulation technique that trains an individual in self-control (and so). Prefrontal cortex) Emotional reaction to clues and contexts encountered by reinterpreting its meaning. For example, the cocaine line in a photo can be reinterpreted as a movie prop that cuts powdered sugar into a line and appears only as cocaine. Cognitive assessment has been adopted in previous studies to reduce participants’ response to drug signals, but the Mount Sinai study is the first to use this technique for regulating emotions in patients. Cocaine addiction On the effect of intentional (undirected, habitual) attention bias on cocaine-related cues.

“Correcting attentional bias has been a fundamental goal for years to reduce recurrence, but it has been elusive,” said Dr Parvaz, director of the Mount Sinai Institute of Psychopathology. Declared. “We found that cognitive reassessment, a function of prefrontal cortex control, reduces spontaneous attentional bias towards drug-related signals in cocaine addicts. In other words, PFC (in the evaluation process). Cognitive control enhanced by cognitive regulation regulates the automatic (difficult to control) attentional process in humans with drug addiction.

“Through our study, it is very difficult to provide a promising framework for ascending automatic self-regulation and resisting drug signal responses, based on the benefits of cognitive reassessment through the prefrontal cortex. Applicable to drug addiction outside the laboratory cocaineProfessor of Psychiatry and Neuroscience, Head of the Neuropsychological Imaging Research Program for Substance Abuse and Related Conditions, and lead author of the article, Dr. Rita Z. Goldstein, said: Intervention strategies used by those who fight drug addiction. Based on empirically validated neuroscience. Contribution to the development of interventions Drug Drug addiction is an important goal of our laboratory. ”


Brain signs predicting vulnerability to drug addiction


For more information:
Muhammad A. Parvaz et al., “Correcting Attention Bias in Drug Poisoning: Further Strengthening of Habits Control” PNAS (2021). www.pnas.org/cgi/doi/10.1073/pnas.2012941118

Quote: Emotional Regulation Techniques May Be Effective In Disrupting Compulsive Cocaine Addiction (May 31, 2021) https://medicalxpress.com/news/2021-05-emotional-technique-effective-disrupting Obtained from -compulsive. html on May 31, 2021

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